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    Organic Synthesis

    Microwave Synthesis

    Chemical reactions proceed more quickly when you heat them. The Arrhenius equation states that for every ten degrees increase in temperature, there is a doubling of the reaction rate. Hence the use of oil baths, heating mantles and reflux condensers in any laboratory involved in chemical synthesis. But in these instances, you are always limited by the boiling point of the solvent you are using, achieving the temperature you need can be slow, and it is difficult to control the temperature and the heating time accurately. Developing ways of improving chemical synthesis is of great benefit.

     

     

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    The Biotage approach – Microwave synthesis

    In the Biotage approach to chemical synthesis, a microwave is employed to heat reactions. Microwave synthesisers have key advantages over traditional synthesis methods with conventional heating. They are extremely fast, as they can be used to super-heat reactions under pressure to higher than their boiling point, greatly accelerating reactions and achieving in minutes what otherwise might require hours. They are green in comparison to older technologies, as they reduce the power input needed compared to heating for many hours. And they are simple to use, giving precise control over a number of parameters such as heating time, temperature and power input.

    Product groups

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    Biotage® Initiator+

    Biotage® Initiator+ represents the latest in microwave synthesis performance. This reliable and upgradeable instrument’s high-end specifications enable the chemist to explore new areas and make great discoveries in less time.

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    Biotage® Initiator+ Microwave System with Robot Eight

    Biotage® Initiator+ can be upgraded from a single-sample manual format to an automated 8-position system. The 8-position sample bed gives the user a compact automation solution to start scale-up process and library build-up, and is useful in a multi-user environment or for queuing multiple reactions. Flexible operation enables the use of both large and small vials in combination at any time and in any order without manual intervention.

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    Biotage® Initiator+ Microwave System with Robot Sixty

    Biotage® Initiator+ can be upgraded from a single-sample manual format to an automated 60-position system. The modular design allows a user to add on different automated sample processors dependent on throughput requirements. The 60-position sample bed supports the production of focused libraries, multi-user environments and scale-out, and use of both large and small vials in any order without manual intervention.

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    Microwave Reaction Vials

    Biotage high precision microwave vials are designed and tested to withstand pressures beyond 30 bar in a wide range of conditions to guarantee durable and safe reactions at all times.

    Resources

    Organic chemists synthesizing new molecules follow a general workflow. Biotage has developed tools for every step of the process, with the entire workflow in mind. This dedicated suite of products vastly expands the range of options in order to truly accelerate discoveries
    of new molecules for future innovations.

    Other blocks in the workflow

    Biotage, pioneers of flash chromatography, has an extensive range of instrumentation and flash consumables designed to make your chemistry more efficient, simpler and greener.

    Biotage evaporation offer is designed for faster evaporation of volatile and high-boiling solvents and sample transfer minimization. Utilizing rotation and vacuum technology, Biotage will automate your evaporation and make it faster, simpler, greener.

    A complete set of tools to speed up traditional work flow processes and also enhance productivity and flexibility in the laboratory.  Faster, Simpler, Greener.