The Biotage® Initiator+ Alstra™ is a fully automated microwave peptide synthesizer that adds speed to your peptide workflow and gives you the flexibility to perform both small and large scale synthesis.
Microwave irradiation is a fast and precise heating method for the synthesis of peptides at elevated temperatures providing dramatic reductions in synthesis time along with an increase in crude purity and yield compared to conventional synthesis methods. With functionality such as the unique Branches™ tool, preactivation, “edit on the fly” as standard and with options for UV monitoring and microwave assisted organic synthesis (MAOS), the Initiator+ Alstra™ allows you to access different peptide chemistries simply and efficiently, speeding up your workflow. As such the system is the ideal tool for synthesizing interesting peptides, peptoids, PNAs and peptidomimetics.
The flexible reagent setup and modular amino acid racks allow rapid adoption of different coupling strategies such as multiple coupling, and capping reagents to be used during a synthesis. The amino acids or reagents can be placed anywhere on the rack tray.
Flexible synthesis scales from 5 μmol - 2 mmol easily accommodates most laboratory synthesis scale requirements giving rapid access to the scale you need. Peptide synthesis is performed in disposable reactor vials which can be simply inserted and removed without requiring cumbersome disconnection of parts. Digital syringe pumps guarantee accurate dispensing of all reagents, and the dual needle design reduces the possibility of cross contamination. The patented oscillating mixing technology (US 9534011) is superior to nitrogen gas bubbling and ensures homogeneous heat distribution and efficient mixing of reagents up to 2 mmol scale synthesis.