Evaluation of Sample Preparation Approaches for the Extraction of Amphetamine, Methamphetamine, MDMA and Metabolites from Urine Prior to GC/MS Analysis

Amphetamine, methamphetamine and Ecstasy continue to be widely abused in many parts of the world. Urine analysis is the most popular approach to determining drug intake. This poster examines various sample preparation approaches in the analysis of amphetamines prior to gas chromatography-mass spectrometry. Comparisons were performed between silica-based and polymer-based SPE (ISOLUTE HCX and EVOLUTE EXPRESS CX) as well as supported liquid extraction (SLE, ISOLUTE SLE+). SOFT 2021. Previous version presented at TIAFT 2019