Practical Considerations Using Oral Fluid Collection Devices and SPE Method Development for Drugs of Abuse and with THC and Metabolites

In this poster we describe the relationship between 85 DOA and their subsequent response to the recovery and matrix effects of Immunalysis' Quantisal buffer as used with water as a surrogate oral fluid, synthetic oral fluid from UTAK, and the Quantisal device. Moreover, we examine the impact upon recovery and matrix effects upon modulating solvent polarity of the organic wash to improve analyte detection and SPE method ruggedness upon a large and diverse panel of analytes.