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    Mixed-Mode SPE

    All the SPE phases on this page extract ionizable analytes from biological fluids using a robust dual retention mechanism, which allows additional wash steps for enhanced extract purity.
    • Extract basic analytes using mixed-mode non-polar/cation exchange sorbents
    • Extract acidic analytes using mixed-mode non-polar/anion exchange sorbents
    cond-equil-load-wash-elute

    Extract basic analytes using combined non-polar and strong cation exchange retention mechanisms.

    ISOLUTE® HCX

    Extract basic analytes using combined non-polar and strong cation exchange retention mechanisms. Strong non-polar character for enhanced recovery of more polar compounds.

    ISOLUTE® HCX-3

    Extract basic analytes using combined non-polar and strong cation exchange retention mechanisms. Reduced non-polar character for higher purity extracts of more hydrophobic compounds.

    ISOLUTE® HCX-5

    Extract strongly basic (e.g. quaternary amine)  analytes using combined non-polar and weak cation exchange retention mechanisms.

    ISOLUTE® HCX-Q

    Extract acidic analytes using combined non-polar and strong anion exchange retention mechanisms.

    ISOLUTE® HAX

    About Biotage

    Biotage is the Global Go-To Separations Company, supporting customers from drug discovery and development through to diagnostics and analytical testing with intelligent and sustainable workflow solutions. Our expertise and top-tier separation solutions play a key role in streamlining our customers’ workflows and improving their outcomes. Headquartered in Sweden, Biotage operates globally with 700 employees, serving over 80 countries. Our company is listed on NASDAQ Stockholm (BIOT).

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    ISOLUTE Mixed-Mode Solid Phase Extraction (SPE)