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    Catecholamines & Metabolites

    Highlighted Applications

    Robust Extraction of Plasma Catecholamines and Metanephrines

    Optimized for clean-up of plasma samples containing a range of anticoagulants, giving robust performance for analysis to <10 pg/mL (<0.05 nmol/L) by LC-MS/MS analysis.


    Automated Extraction of Urinary Catecholamines and Metanephrines

    A robust, mixed-mode weak cation exchange SPE protocol for the extraction of catecholamine and metanephrine metabolites from urine prior to LC-MS/MS detection. Fully automatable  for high throughput assays, the method can prepare 96 samples in 52 minutes.


    Acidic Catecholamine Metabolites in Plasma (VMA, HVA, 5-HIAA)

    A simple ‘load-wait-elute’ supported liquid extraction methodology for the acidic metabolites, for LC-MS/MS analysis in the range of 5-200 mg/mL.


    Automated Extraction of Plasma ‘Cats & Mets’ using Microelution SPE

    Microelution format methodology using mixed-mode weak cation exchange SPE, automated using the Biotage® Extrahera™ LV-200. This robust method can extract 96 samples in approximately 60 minutes.


    This application is also available in 10 mg format.



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