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Is reversed-phase flash chromatography less expensive than normal-phase?
Small Molecules and Synthetic Therapeutics
This post compares the cost differences between reversed-phase and normal-phase flash chromatography.
How can I dry my temperature-sensitive product without degradation?
Small Molecules and Synthetic Therapeutics
This post discusses the efficiency of low temperature evaporation of solvents with boiling points 100 C and higher.
Does flash column equilibration volume impact purification results?
Small Molecules and Synthetic Therapeutics
This post discusses the impact of column equilibration volume of chromatography results.
What is the maximum volume I can load on my reversed-phase flash column?
Small Molecules and Synthetic Therapeutics
This post discusses the impact of that sample solvent on the loading capacity of a reversed-phase flash column.
Can dry load media choice impact normal-phase flash purification quality?
Small Molecules and Synthetic Therapeutics
This post discusses the benefits obtainable using dry loading vs. liquid loading.
Does Detection Wavelength Influence Compound Purity and Recovery?
Small Molecules and Synthetic Therapeutics
This post discusses whether a single or multiple fractionation wavelengths generate higher purity in greater amounts.
When should I use a “high-performance" flash chromatography column?
Small Molecules and Synthetic Therapeutics
This post discusses the benefits achievable when using a “high-performance" flash chromatography column.
TLC-based vs. Generic Gradients – Which Gives the Best Results?
Small Molecules and Synthetic Therapeutics
This post compares TLC-based gradients to a generic linear gradient to highlight the benefits TLC provides.
Ionizable compound purification using reversed-phase flash column chromatography
Small Molecules and Synthetic Therapeutics
This post discusses how ionizable compounds can be purified using reversed-phase flash column chromatography.
Does a longer flash column really provide better purification?
Small Molecules and Synthetic Therapeutics
This post discusses the relationship between column length and column diameter and their impact of chromatographic separations.
