Part No: IST1086SIssued year: 2006File size: 0.03mbFile type: pdf
The following method describes the extraction and separation of non-conjugated parent, glucuronide conjugates and sulfate conjugates of a proprietary pharmaceutical from urine and bile using non-polar and anion exchange mechanisms.
Part No: IST1072SIssued year: 2006File size: 0.03mbFile type: pdf
This method describes the extraction of quaternary amines, strongly basic amines and amines that are unstable at high pH levels, from biological fluids. The mechanism is mixedmode
hydrophobic and weak cation exchange, allowing acidic elution conditions.
Part No: AN-IST1004SIssued year: 2008File size: 0.04mbFile type: pdf
This method describes a procedure for the determination of Total Oil and Grease using IR as the technique for final analysis. This represents recommendations for SPE method development. The proposed steps are based on experience with similar analytes and matrices, but have not been verified in Biotage laboratories. Please refer to section below for the analyte and matrix considerations that were made in developing this method. As for all method development, this procedure should first be developed using pure solvent spiked with analyte. Only after the chemistry is established should spiked matrix samples be tested.
Part No: AN-IST1009SIssued year: 2008File size: 0.04mbFile type: pdf
This method describes the use of a strong cation exchange SPE column for the extraction of pyridoxine, riboflavin and thiamine from biological fluid samples. This represents recommendations for SPE method development. The proposed steps are based on experience with similar analytes and matrices, but have not been verified in Biotage laboratories. Please refer to section below for the analyte and matrix considerations that were made in developing this method. As for all method development, this procedure should first be developed using pure solvent spiked with analyte. Only after the chemistry is established should spiked matrix samples be tested.
Part No: F0101504_01Issued year: 2015File size: 0.4mbFile type: pdf
Oil and Grease is an important general measurement that can be used to indicate water quality and help ensure consistent wastewater treatment plant operation.
Automated solid phase extraction can help to make the process more reproducible and easier to fit into the laboratory workflow. The SPE-DEX 3100 offers reliable operation, even with highly particulated samples.
Part No: B0041504_02bIssued year: 2015File size: 4.68mbFile type: pdf
Oil and grease (n-hexane extractable
material) is a general indicator of the
amount of hydrocarbons in a water
supply. The SPE-DEX 3100 automates the entire extraction
process, fully compliant with US EPA Method
1664A/B, ISO 11349 and Standard Methods 5520B.
Part No: TN0161703_02Issued year: 2017File size: 0.5mbFile type: pdf
The SPE-Z Prep manifold is a low-cost solution for disk solid phase extraction (SPE). The SPE-Z Prep manifold simultaneously processes up to 3 samples with easy-to-use rugged hardware. The multipurpose funnel (shown in Figure 1) allows easy sample loading with a variety of sample bottles and disk holder combinations on a single system. The SPE-Z Prep manifold allows the use of SPE disks instead of liquid-liquid extraction, increasing efficiency, especially since the possibility of an emulsion forming is greatly reduced.
Part No: PPS347Issued year: 2014File size: 0.49mbFile type: pdf
Trends on chemical synthesis have changed over recent years, with a more targeted approach to molecular design becoming more prevalent. As a result, the speed with which a new compound can be synthesized is key to an efficient laboratory.
Part No: F0051403_01Issued year: 2014File size: 0.14mbFile type: pdf
The Speed-Vap IV is a modern evaporation system providing safe and simultaneous unattended evaporation of up to nine pans of evaporating solvent for extractable hydrocarbons such as hexane oil and grease extractions generated using methods such as US EPA 1664, ISO 11349:2010 or Standard Methods 5520. It can also be used to evaporate solvents from extracted soil hydrocarbons and fats from foods.
Part No: TN522Issued year: 2004File size: 0.03mbFile type: pdf
Microwave assisted organic synthesis has become an important tool to medicinal chemists for rapid organic synthesis. Thousands of research papers have appeared over the last decades on the application of microwave technology in organic synthesis.1 Some of the major advantages include a spectacular decrease in reaction time, improved conversions, clean product formation and wide scope for the development of new reaction conditions.
Part No: Issued year: 2002File size: 0.36mbFile type: pdf
The first decision that needs to be made is what the final analysis will be for the analyte. This will have an impact on the sample and cartridge size, as well as the final elution solvent. Gas chromatography offers higher sensitivity than HPLC, while HPLC is better suited for ionisable species and very high molecular weights. If LC-MS is available, minimal sample clean-up may be required.
Part No: P167Issued year: 2017File size: 0.42mbFile type: pdf
For most organic and natural product chemists flash
chromatography is a necessary part of their research. As such, many chemists need quick isolation of at least one desired component from a crude mixture in relatively high yield and purity. This need for speed, purity, and yield pits these desires against each other as you can typically optimize on only two of the three goals.
In this poster, we will describe some techniques that help chemists optimize flash purification and maximize speed, yield, and purity.