This Application Note reviews the use of ISOLUTE PPT+ plates for the isolation of drugs from biological fluids, including the method, recovery data and the impact of the filtrate’s cleanliness on analyte quantitation.

Application Notes

English Manuals & User Guides

Manuals & User Guides

Isolera™ Dalton System Care Guide

English Manuals & User Guides

The mass-directed flash purification system Isolera™ Dalton produces its final mass spectrum by compiling data from hundreds of individual mass spectra in real time.

Product Notes

The direct injection kit is intended to be used to inject samples into Isolera™ Dalton Nanolink using a syringe with a Luer-Lok tip.

English Manuals & User Guides

English Manuals & User Guides

Manuals & User Guides

English Release Notes

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How to Install Isolera SW 2.3

Manuals & User Guides

English Manuals & User Guides

Be sure you have your target compound the moment your purification is complete. The Isolera™ Dalton integrates the Biotage approach to flash chromatography with true compound identification using mass detection.

Brochures

Traditional RP-HPLC techniques not always critical because improvements in solid-phase peptide synthesis techniques over the years (microwave heating and ChemMatrix® solid phase supports) have reduced the burden on downstream purification steps. Mass directed flash purification can be a viable alternative to more expensive (and lower capacity) semi- or prep-scale RP-HPLC methods.

Application Notes

This document outlines service products specific to Isolera™ Dalton. For further information on Biotage service products please see “Biotage Service Agreements” brochure (PPS330).

Product Notes

Isolera Dalton identifies compounds by mass in real time during flash separation, leading to greater confidence in purification, higher purity, greater recovery, and a significant saving in time. Reduce or eliminate the need for time consuming off-line mass analysis during development programs, increase throughput and effectiveness for both chemists and analytical groups.

Product Notes

The Isolera ELSD (evaporative light-scattering detector) is a universal detector designed for use with Isolera flash purification systems when purifying organic compounds that are undetectable UV or visible light. Flash chromatography with detection and fractionation is now possible when purifying carbohydrates, steroids, lipids, terpenes and other UVtransparent compounds.

Product Notes

Isolera™ is a new, more compact, flash purification system with intelligent features that enable chemists to easily achieve better separations.

Product Notes

The Isolera leak detection system is designed with safety in mind. Unlike vapor sensing devices with unreliable solvent vapor sensitivity, the Isolera leak detector’s sensitive, solvent-resistant refractive index (RI) monitor rapidly signals the Isolera flash system to stop pumping if any liquid, volatile or non-volatile, is detected thus protecting the chemist, system, and lab from potential hazards.

Manuals & User Guides Product Notes

TheBiotage Isolera™LS development-scale flash purification systemdramatically shortens large-scale purification run-times with flow rates of 50-500mL/minute. Simply select or create a method, load your sample, and run – it’s that easy. New advanced features include: solvent-savingGradientOptimization (GO), the ability to collect fractions on two separatewavelengths, use of up to four solvents in a single gradient and add a third isocratic co-solvent.

Product Notes