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    Documents | Extraction of Buprenorphine and Norbuprenorphine from Urine Using EVOLUTE® EXPRESS CX Prior to LC-MS/MS Analysis

    Extraction of Buprenorphine and Norbuprenorphine from Urine Using EVOLUTE® EXPRESS CX Prior to LC-MS/MS Analysis

    This application note describes a simple and robust mixed mode cation exchange solid phase extraction protocol using EVOLUTE® EXPRESS CX 96 well plates for the extraction of buprenorphine and norbuprenorphine from urine. Excellent extract cleanliness allows low level quantitation (0.1 ng/mL) of the analytes using LC-MS/MS.

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