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    Documents | Extraction of Illicit and Prescribed Drugs from Enzyme-Hydrolyzed Urine Using ISOLUTE® HYDRO DME+ Prior to UPLC-MS/MS Analysis

    Extraction of Illicit and Prescribed Drugs from Enzyme-Hydrolyzed Urine Using ISOLUTE® HYDRO DME+ Prior to UPLC-MS/MS Analysis

    This application note describes the extraction of 25 illicit and prescribed drugs from hydrolyzed urine using ISOLUTE® HYDRO DME+ Dual Mode Extraction plates prior to UPLC-MS/MS analysis. Because of the enhanced sample clean up delivered by ISOLUTE HYDRO DME+ products, analyte sensitivity is significantly increased compared to traditional dilute and shoot (D&S) techniques, resulting in reduced limits of quantitation (LOQ)

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