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    Documents | Sample Preparation Method for Determination of Voriconazole in Plasma Using ISOLUTE® SLE+

    Sample Preparation Method for Determination of Voriconazole in Plasma Using ISOLUTE® SLE+

    Voriconazole (Figure 1) is a triazole-based antifungal drug that is widely used to treat fungal infections, including invasive aspergillosis, pulmonary aspergilloma, and candidemia. However, because side effects such as prolonged QT syndromes, toxic epidermal necrolysis, and anaphylaxis are known, it is included in Therapeutic Drug Monitoring (TDM) regimes. This application note proposes a method that can be used for both UV and LC-MS/MS measurements.

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