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Designed polymers are a class of selective resins with engineered selectivities for particular target molecules or ‘classes’ of molecules. These designed polymers are obtained by careful tuning of their surface chemistry and morphology which allows them to exhibit unique separation capabilities. The tailored and optimized selectivity of designed polymers is utilized to conduct difficult separations that are not able to be accomplished with conventional separation resins or other techniques.

Posters

This application note describes the extraction of a panel of estrogenic hormones from human serum using EVOLUTE® EXPRESS ABN solid phase extraction plates prior to LC/MS analysis. The simple sample preparation procedure delivers clean extracts and analyte recoveries greater than 90% with RSDs lower than 5% for all analytes. Linearity of greater than 0.99 is achieved for Estrone (E1) and Estradiol (E2) from 5–2000 pg/mL, and 50–20000 pg/mL for Estriol (E3). No derivatization is required, and detection limits are enhanced using a fluorinated mobile phase.

96-well plate Application Notes Clinical English Estradiol Estriol Estrogens Estrone LC-MS/MS Serum Steroid Steroid Hormones

Monitoring estrogenic compounds such as Estrone (E1), Estradiol (E2), and Estriol (E3) in human serum is essential in clinical research and diagnostics. Detection in men, post-menopausal women and children requires very low limits of detection (LODs) which can be challenging.

96-well plate Clinical Estrogens LC-MS/MS Posters Serum

This application note demonstrates the performance of the Biotage® Horizon 5000 automated solid phase extraction system for extraction of 1,4-dioxane from drinking water, in compliance with US EPA Method 522.

1,4-dioxane Application Notes Column Drinking water EPA 522 Analytes English Environmental Environmental contaminants GC-MS US EPA Method 522 Water

This paper demonstrates how the introduction of simple automated technology and a modification in analysis. Can positively impact analytical results and overall throughput for critical environmental testing.

Application Notes Environmental GC-MS Organophosphate Pesticide

Carbaryl, a commonly used insecticide for the past 20 years, has become a significant environmental concern throughout the world. Also known through its trademarked name Sevin, it is a cholinesterase inhibitor and can be toxic to humans, causing problems in the blood, nervous, and reproductive systems.

4790 Application Notes Disk Drinking water English Environmental Insecticides Pesticides

Deoxynivalenol is a common mycotoxin found in agricultural grain crops and final consumer processed products. Most impacted are wheat, barley, and corn. Deoxynivalenol, also known as Vomitoxin, is produced by Fusarium fungi and has a unique dual-stage growth cycle of producing mold during warm daylight and toxin during cool nights. There is no known procedure or processing that will remove deoxynivalenol that is already present in grain.

Application Notes Deoxynivalenol (DON) English Food Food Mycotoxin SmartPrep

Hormones in drinking water are a growing concern, since the presence of these compounds can potentially be linked to serious health hazards such as human developmental and reproductive side-effects. Hormones are introduced into our environment in several ways. Natural and synthetic hormones that are given to livestock, pass though the animals, runoff into surface water, and leach into underground water supplies. Humans also produce and excrete natural hormone waste every day.

4790 Androgens Clinical Disk Drinking water Endocrine disrupter English Estrogens Hormones

The second Unregulated Contaminant Monitoring Regulation (UCMR2) program was developed to monitor US drinking water sources for currently unregulated compounds. EPA Method 529 is categorized under List 1, Assessment Monitoring in the UCMR2 program, and focuses on three explosives: 1,3-dinitrobenzene; 2,4,6- trinitrotoluene (TNT); and hexahydro-1,3,5-trinitro-1,3,5- triazine (RDX). The resulting data will be used by the EPA to determine whether or not regulatory standards should be established for these compounds.

1,3,5-trinitrobenzene 1,3-dinitrobenzene 2,4,6-trinitrotoluene (TNT) 2-amino-4,6-dinitrotoluene 2-nitrotoluene 3,5-dinitroaniline 3-nitrotoluene 4-amino-2,4-dinitrotoluene Application Notes Disk English Environmental Explosives GC/MS/MS RDX SUR_1,2,4-trimethyl-5-nitrobenzene SUR_1,3,5-trimethyl-2-nitrobenzene SUR_Nitrobenzene-d5

At present, pollution of freshwater algae has become aglobal environmental problem. Of all the different pollution types, microcystin LR is the most toxic and the most acute hazard as far as is known presently

4790 Application Notes English Environmental HPLC Micocystins Water